Role of fiber diameter in adhesion and proliferation of NIH 3T3 fibroblast on electrospun polycaprolactone scaffolds.

@article{Chen2007RoleOF,
  title={Role of fiber diameter in adhesion and proliferation of NIH 3T3 fibroblast on electrospun polycaprolactone scaffolds.},
  author={Ming Chen and Prabir Patra and Steven B. Warner and Sankha Bhowmick},
  journal={Tissue engineering},
  year={2007},
  volume={13 3},
  pages={579-87}
}
The goal of the current study was to find the quantitative relationship between electrospun polycaprolactone scaffold fiber diameter and NIH 3T3 fibroblast adhesion and growth kinetics. By varying 3 important process parameters--solution concentration, voltage, and collector screen distance--different average fiber diameters ranging from 117 to 1,647 nm were obtained. Although 117 nm represented the lowest possible fiber diameter obtainable, these fibers had beads in them. An increase in fiber… CONTINUE READING

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