Role of familiarity versus interleukin-1 genes cluster polymorphisms in chronic periodontitis.

@article{Zuccarello2014RoleOF,
  title={Role of familiarity versus interleukin-1 genes cluster polymorphisms in chronic periodontitis.},
  author={Daniela Zuccarello and M Federica Bazzato and Alberto Ferlin and Manuel Pengo and Anna Chiara Frigo and Giovanni Favero and C Foresta and Edoardo Stellini},
  journal={Gene},
  year={2014},
  volume={535 2},
  pages={286-9}
}
Periodontitis (PO) is a multifactorial disease affecting about 10% to 20% of the general population. Several studies have suggested that part of the clinical variability in PO might be explained by genetic factors. Among the candidate genes for PO, IL1 gene polymorphisms have been broadly investigated, with variable results, for their relationship with the disease. We studied three IL1 polymorphisms, IL1A C[-889]T (rs1800587), IL1B C[3953/4]T (rs1143634), and IL1RN VNTR [+2018] (rs419598) in… CONTINUE READING

References

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Polymorphisms in the interleukin-1 (IL1) gene cluster are not associatedwith aggressive periodontitis in a large Caucasian population

  • A Fiebig
  • Genomics
  • 2008
Highly Influential
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