Role of experience in acquisition and loss of tolerance to the effect of delta-9-THC on spaced responding.

@article{Manning1976RoleOE,
  title={Role of experience in acquisition and loss of tolerance to the effect of delta-9-THC on spaced responding.},
  author={Frederick J. Manning},
  journal={Pharmacology, biochemistry, and behavior},
  year={1976},
  volume={5 3},
  pages={269-73}
}
Albino rats were given extensive training in spaced responding, using a DRL 30 sec schedule of food reinforcement (only lever presses more than 30 sec apart were reinforced). All rats then went 12 days without behavioral testing. During this period half the rats received daily intragastric doses of delta-9-tetrahydrocannabinol (THC) and the rest equal volumes of the THC vehicle. On day 13, some rats received THC 3 hr before behavioral testing while others received only vehicle. The former… CONTINUE READING

From This Paper

Topics from this paper.

Similar Papers

Loading similar papers…