Role of executive function in late-life depression.

@article{Alexopoulos2003RoleOE,
  title={Role of executive function in late-life depression.},
  author={George S. Alexopoulos},
  journal={The Journal of clinical psychiatry},
  year={2003},
  volume={64 Suppl 14},
  pages={18-23}
}
Late-onset depression has been conceptualized as a neurologic disease. This view has been supported by studies suggesting that late-onset depression is associated with cognitive impairment and neurologic comorbidity that may or may not be clinically evident when depression is first diagnosed. Findings implicating a dysfunction of frontostriatal-limbic pathways in geriatric depression have led to the depression-executive dysfunction (DED) syndrome hypothesis. Subsequent studies suggested that… CONTINUE READING

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