Role of estrogen receptor α and β in the induction of progesterone receptors in hypothalamic ventromedial neurons.

@article{S2013RoleOE,
  title={Role of estrogen receptor α and β in the induction of progesterone receptors in hypothalamic ventromedial neurons.},
  author={Susana Isabel S{\'a} and Pedro Alberto Pereira and Viacheslav Malikov and Maria Dulce Cordeiro Madeira},
  journal={Neuroscience},
  year={2013},
  volume={238},
  pages={
          159-67
        }
}
The estrogen induction of progesterone receptors (PRs) in the ventrolateral division of the hypothalamic ventromedial nucleus (VMNvl) is critical for the regulation of female sexual behavior. VMNvl neurons express PRs and both types of estrogen receptors (ERα and ERβ), and their sequential activation initiates the molecular mechanisms underlying sexual behavior. To assess the relative importance of each ER subtype in the induction of PRs, we have estimated the total number of PR-immunoreactive… CONTINUE READING

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