Role of estrogen in controlling the genital microflora of female rats

@article{Larsen1977RoleOE,
  title={Role of estrogen in controlling the genital microflora of female rats},
  author={Bryan Larsen and A. J. Markovetz and Rudolph P. Galask},
  journal={Applied and Environmental Microbiology},
  year={1977},
  volume={34},
  pages={534 - 540}
}
Plate counts of viable bacteria recovered by lavage from rat vaginae demonstrated that the number of bacteria associated with the vaginal epithelium varied cyclically and that this pattern was abolished by ovariectomy. After ovariectomy, vaginal bacterial counts remained relatively stable at low levels. The estrogen 17beta-estradiol (1,3,5(10)-estratriene-3,17beta-diol cypionate) administered to ovariectomized rats caused a significant increase in vaginal bacterial counts on day 3 post… 

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