Role of epithelial ion transports in inflammatory bowel disease.

  title={Role of epithelial ion transports in inflammatory bowel disease.},
  author={Diogo Magalh{\~a}es and Jos{\'e} Miguel Cabral and Patr{\'i}cio Soares-da-Silva and Fernando Magro},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  volume={310 7},
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder with a complex pathogenesis. Diarrhea is a highly prevalent and often debilitating symptom of IBD patients that results, at least in part, from an intestinal hydroelectrolytic imbalance. Evidence suggests that reduced electrolyte absorption is more relevant than increased secretion to this disequilibrium. This systematic review analyses and integrates the current evidence on the roles of epithelial Na(+)-K(+)-ATPase (NKA), Na… CONTINUE READING
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