Role of epidermal growth factor in bovine oocyte maturation and preimplantation embryo development in vitro.

@article{Lonergan1996RoleOE,
  title={Role of epidermal growth factor in bovine oocyte maturation and preimplantation embryo development in vitro.},
  author={Pat Lonergan and Catherine Carolan and Anne van Langendonckt and Isabelle Donnay and H Khatir and Pascal Mermillod},
  journal={Biology of reproduction},
  year={1996},
  volume={54 6},
  pages={
          1420-9
        }
}
  • Pat Lonergan, Catherine Carolan, +3 authors Pascal Mermillod
  • Published in Biology of reproduction 1996
  • Biology, Medicine
  • Epidermal growth factor (EGF) has been shown to have a positive effect during in vitro maturation (IVM) and has been reported in follicular fluid at levels capable of stimulating meiosis in a variety of species. The aim of the present work was to study the effect on subsequent development of EGF present in defined medium during bovine 1) oocyte maturation or 2) embryo culture. The presence of EGF during IVM, irrespective of concentration (1, 10, 100 ng/mg), stimulated cumulus expansion and… CONTINUE READING

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