Role of epidermal growth factor in bovine oocyte maturation and preimplantation embryo development in vitro.

@article{Lonergan1996RoleOE,
  title={Role of epidermal growth factor in bovine oocyte maturation and preimplantation embryo development in vitro.},
  author={P. Lonergan and C. Carolan and A. van Langendonckt and I. Donnay and H. Khatir and P. Mermillod},
  journal={Biology of reproduction},
  year={1996},
  volume={54 6},
  pages={
          1420-9
        }
}
Epidermal growth factor (EGF) has been shown to have a positive effect during in vitro maturation (IVM) and has been reported in follicular fluid at levels capable of stimulating meiosis in a variety of species. The aim of the present work was to study the effect on subsequent development of EGF present in defined medium during bovine 1) oocyte maturation or 2) embryo culture. The presence of EGF during IVM, irrespective of concentration (1, 10, 100 ng/mg), stimulated cumulus expansion and… Expand
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Effect of EGF on in vitro maturation of domestic cat oocytes.
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