Role of endotoxin in intestinal reperfusion-induced expression of E-selectin.

  title={Role of endotoxin in intestinal reperfusion-induced expression of E-selectin.},
  author={Philippe Bauer and J. M. Russell and Dr. D. Neil Granger},
  journal={The American journal of physiology},
  volume={276 2 Pt 1},
Products of enteric bacteria, including endotoxin [lipopolysaccharide (LPS)], have been implicated in the acute inflammatory responses elicited by ischemia and reperfusion (I/R) of the small intestine. The objective of this study was to assess the contribution of LPS to the increased E-selectin expression observed in the intestinal vasculature after I/R. The dual radiolabeled monoclonal antibody technique was used in LPS-sensitive (C3HeB/FeJ) and LPS-insensitive (C3H/HeJ) mice that were exposed… CONTINUE READING


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