Role of endothelial dysfunction in coronary artery disease and implications for therapy.

@article{Kinlay1997RoleOE,
  title={Role of endothelial dysfunction in coronary artery disease and implications for therapy.},
  author={Scott Kinlay and Patricia Ganz},
  journal={The American journal of cardiology},
  year={1997},
  volume={80 9A},
  pages={
          11I-16I
        }
}
Atherosclerosis is a complex process that is characterized by the accumulation of modified low-density lipoprotein (LDL), local inflammatory and immune responses, and reduced nitric oxide bioavailability within the arterial wall. These cellular changes lead to endothelial vasomotor dysfunction, plaque instability, and the development of clinical events such as stable angina and the acute coronary syndromes. The vascular endothelium plays a critical role in modulating both the inflammatory… CONTINUE READING
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