Role of endothelial cells in relaxation of isolated arteries by bradykinin.

@article{Cherry1982RoleOE,
  title={Role of endothelial cells in relaxation of isolated arteries by bradykinin.},
  author={P D Cherry and Robert F. Furchgott and John V. Zawadzki and D Jothianandan},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1982},
  volume={79 6},
  pages={2106-10}
}
Bradykinin elicits relaxation of isolated transverse rings of canine coronary, celiac, superior mesenteric, renal, splenic, pulmonary, gastric, and femoral arteries. After endothelial cells of the vessel wall are removed by rubbing of the intimal surface, canine arteries fail to relax upon addition of bradykinin. The endothelium-dependent relaxation of canine arteries remains intact after treatment with cyclooxygenase inhibitors (indomethacin and flurbiprofen), and this argues against mediation… CONTINUE READING
77 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 77 extracted citations

Similar Papers

Loading similar papers…