Role of endoscopy and biopsy in the work up of dyspepsia

  title={Role of endoscopy and biopsy in the work up of dyspepsia},
  author={Guido N. J. Tytgat},
  pages={iv13 - iv16}
Endoscopy is recommended as the first investigation in the work up of a patient with dyspeptic symptoms and is essential in the classification of the patient's condition as organic or functional dyspepsia. Although the correlation between mucosal alterations and symptom pattern is difficult, endoscopy will remain the initial investigation of choice for clinically relevant abnormalities that need proper detection and biopsy. 
Endoscopic Evaluation of Patients with Dyspepsia in a Tertiary Care Hospital
It was concluded that dyspepsia is a common clinical condition encountered in day to day practice and endoscopy plays a major role in the management.
Guidance on the effective use of upper gastrointestinal histopathology
There are clear indications to biopsy suspicious ulceration or mass lesions and for investigation of some inflammatory conditions, such as eosinophilic oesophagitis and coeliac disease, but outside these areas, the endoscopist should consider whether biopsy of normal or abnormal appearing mucosa is likely to contribute to patient management, to ensure effective use of limited healthcare resources.
Diffi culties of diff erential diagnosis in functional dyspepsia
The diagnosis of PD should be considered as a diagnosis of exclusion, which can be made only after a comprehensive examination of patients, and the recommendations of the Russian Gastroenterological Association emphasize that this approach leads to serious diagnostic errors.
Endoscopic Findings in Persistent Dyspepsia in Secondary Care Hospital Setting in North Kashmir.
The endoscopic diagnosis of persistent dyspepsia in this setting showed a predominance of functional disease, whereas UGI malignancy was an uncommon finding.
[Diagnosis of functional dyspepsia: a systematic review].
This review tried to set up an initial diagnostic strategy in patients with functional dyspepsia. Dyspepsia was defined as chronic or recurrent pain, or discomfort centered in the upper abdomen
Evaluation of Dyspepsia with Upper Gastrointestinal Endoscopy-Single Centre Study from South India
Endoscopy is the diagnostic procedure of choice in the evaluation of upper gastrointestinal symptoms and remains the “gold standard” by evaluating all cases of dyspepsia by scopy and serious pathology like malignancy may not be missed at earlier stage thus reducing morbidity and mortality.
Low Prevalence of Clinically Significant Endoscopic Findings in Outpatients with Dyspepsia
Dyspeptic patients have low prevalence of SEFs and the presence of any alarm feature and age ≥ 55 are associated with higher risk of SEF; these patients can be considered for nonendoscopic approach for diagnosis and management.
Functional dyspepsia in Yola, Nigeria
Dyspepsia is a common disorder originating from the upper gastrointestinal tract, and is the most common indication for gastrointestinal endoscopy, and it has profound clinical and economic effects, and influences the quality of life of sufferers.
Duodenal lymphocytosis in functional dyspepsia.
  • A. Capannolo, S. Necozione, G. Frieri
  • Medicine
    Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology
  • 2019


Evaluation of one-visit endoscopic clinic for patients with dyspepsia.
Instant endoscopy with a small-diameter endoscope provides a convenient and fast primary diagnostic service for patients with dyspepsia and its acceptability was high for both patients and doctors.
Endoscopic studies of dyspepsia in a general practice.
In an urban general practice serving 7800 patients, all patients presenting over five and a half years with dyspepsia lasting more than two weeks were investigated by fibreoptic endoscopy and cholecystography, and many by barium meal, suggesting that such endoscope services are indeed worth while for providing an accurate diagnosis of dyspepsy.
The clinical benefit of routine upper gastrointestinal endoscopy.
The present study supports the widespread use of upper gastrointestinal endoscopy in clinical practice and shows that about half of the endoscopies disclosed clinically significant abnormalities.
Endoscopic findings in patients with ulcer-like dyspepsia.
The clinical findings of presence of night pain, pain relief after food intake and history of peptic ulcer were more common in patients with an existing peptic Ulcer than in those with a normal endoscopy.
The predictive value of history in dyspepsia.
In general, the low prevalence of organic diseases resulted in low positive and high negative predictive values, which may be to reduce the number of negative endoscopies rather than to predict a precise diagnosis.
Etiology of dyspepsia: four hundred unselected consecutive patients in general practice.
The latest classification of functional dyspepsia is not in accordance with the symptom complex and it is concluded that functional disorders, when symptomatic gastroesophageal reflux was included, were diagnosed in 55%.