Role of endoplasmic reticulum stress in drug‐induced toxicity

  title={Role of endoplasmic reticulum stress in drug‐induced toxicity},
  author={Fabienne Foufelle and Bernard Fromenty},
  booktitle={Pharmacology research & perspectives},
Drug-induced toxicity is a key issue for public health because some side effects can be severe and life-threatening. These adverse effects can also be a major concern for the pharmaceutical companies since significant toxicity can lead to the interruption of clinical trials, or the withdrawal of the incriminated drugs from the market. Recent studies suggested that endoplasmic reticulum (ER) stress could be an important event involved in drug liability, in addition to other key mechanisms such… CONTINUE READING
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