Corpus ID: 42214131

Role of endogenous prostaglandins in secretin- and plaunotol-induced inhibition of gastric acid secretion in the rat.

@article{Shiratori1993RoleOE,
  title={Role of endogenous prostaglandins in secretin- and plaunotol-induced inhibition of gastric acid secretion in the rat.},
  author={K. Shiratori and S. Watanabe and T. Takeuchi},
  journal={The American journal of gastroenterology},
  year={1993},
  volume={88 1},
  pages={
          84-9
        }
}
We investigated the role of endogenous prostaglandins in the inhibitory effect of exogenous secretin and the antiulcer agent plaunotol on gastric acid secretion in the rat. Intravenous infusion of secretin (0.05 CU/kg/h) and intraduodenal administration of the secretin-releasing agent, plaunotol (320 mg/h), resulted in significant inhibition of gastric acid secretion stimulated by intravenous infusion of pentagastrin (0.3 micrograms/kg/h), and this was accompanied by an increase in the… Expand
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  • J.Y.S. CHU, W.H. YUNG, B.K.C. CHOW
  • Biology, Medicine
  • Annals of the New York Academy of Sciences
  • 2006
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