Role of endogenous opioid peptides in protection of ischemic preconditioning in rat small intestine.

@article{Zhang2001RoleOE,
  title={Role of endogenous opioid peptides in protection of ischemic preconditioning in rat small intestine.},
  author={Yanfeng Zhang and Yun Xia Wu and Y B Hao and Ying Dun and Shiang P. Yang},
  journal={Life sciences},
  year={2001},
  volume={68 9},
  pages={1013-9}
}
This study investigated the protective effects of ischemic preconditioning on intestinal ischemic injury and the role of endogenous opioid peptides (EOP) in these effects. Ischemia-reperfusion (I/R) induced by 30-min of ischemia and 60-min of reperfusion significantly increased the levels of malondialdehyde (MDA) and lactate dehydrogenase (LDH) and resulted in serious intestinal edema (wet weight/dry weight). The ischemic preconditioning (PC) elicited by three 8-min occlusion periods… CONTINUE READING
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