Role of endogenous cardiotonic steroids in sodium homeostasis.

  title={Role of endogenous cardiotonic steroids in sodium homeostasis.},
  author={W. Schoner and Georgios Scheiner-Bobis},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  volume={23 9},
Consumption of an excess of salt over many years leads to arterial hypertension [1]. This process is accompanied by the activation of a great number of genes involved in the remodelling and hypertrophy of the heart, kidneys and the wall of the arteries. These sodium-induced alterations lead to a higher incidence of stroke, greater stiffness of conduit arteries and enhanced activity of resistance arteries [1–3]. Increased uptake of sodium from the diet may not, in some persons, affect the levels… CONTINUE READING