Role of endogenous and exogenous ligands for the peroxisome proliferators activated receptors alpha (PPAR-α) in the development of inflammatory bowel disease in mice

@article{Cuzzocrea2004RoleOE,
  title={Role of endogenous and exogenous ligands for the peroxisome proliferators activated receptors alpha (PPAR-α) in the development of inflammatory bowel disease in mice},
  author={Salvatore Cuzzocrea and Rosanna D I Paola and Emanuela Mazzon and T. Genovese and Carmelo Mui{\`a} and Tommaso Centorrino and Achille Patrizio Caputi},
  journal={Laboratory Investigation},
  year={2004},
  volume={84},
  pages={1643-1654}
}
The peroxisome proliferator-activated receptor-α (PPAR-α) is a member of the nuclear receptor superfamily of ligand-dependent transcription factors related to retinoid, steroid and thyroid hormone receptors. The aim of the present study was to examine the effects of endogenous and exogenous PPAR-α ligand on the development of experimental colitis. To address this question, we used an experimental model of colitis, induced by dinitrobenzene sulfonic acid (DNBS). When compared to DNBS-treated… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 56 references

5 - Amino isoquinolinone , a potent inhibitor of poly ( adenosine 5 0 - diphosphate ribose ) polymerase , reduces myocardial infarct size

NS Wayman, MC McDonald, Threadgill
Eur J Pharmacol • 2001

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