Role of endochondral ossification of articular cartilage and functional adaptation of the subchondral plate in the development of fatigue microcracking of joints.

@article{Muir2006RoleOE,
  title={Role of endochondral ossification of articular cartilage and functional adaptation of the subchondral plate in the development of fatigue microcracking of joints.},
  author={Peter Muir and Jenna McCarthy and Catherine L Radtke and Mark D. Markel and Elizabeth M. Santschi and Mary C Scollay and Vicki L. Kalscheur},
  journal={Bone},
  year={2006},
  volume={38 3},
  pages={342-9}
}
The mechanisms that regulate functional adaptation of the articular ends of long bones are poorly understood. However, endochondral ossification of articular cartilage and modeling/remodeling of the subchondral plate and epiphyseal trabeculae are important components of the adaptive response. We performed a histologic study of the distal end of the third metacarpal/metatarsal bone of Thoroughbreds after bones were bulk-stained in basic fuchsin and calcified sections were prepared. The… CONTINUE READING

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