Role of efflux pumps inhibitor in decreasing antibiotic resistance of Klebsiella pneumoniae in a tertiary hospital in North India.

@article{Filgona2015RoleOE,
  title={Role of efflux pumps inhibitor in decreasing antibiotic resistance of Klebsiella pneumoniae in a tertiary hospital in North India.},
  author={Joel Filgona and Tuhina Banerjee and Shampa Anupurba},
  journal={Journal of infection in developing countries},
  year={2015},
  volume={9 8},
  pages={815-20}
}
INTRODUCTION The contribution of efflux systems to drug resistance in Enterobacteriaceae is becoming increasingly appreciated. This study phenotypically analyzed the role of efflux mechanisms in resistance to ertapenem, doripenem, and tigecycline among clinical isolates of carbapenem-resistant Klebsiella pneumoniae (CRKP). METHODOLOGY Multidrug-resistant and carbapenem non-susceptible K. pneumoniae isolates were determined by disk diffusion test. Further susceptibility of these isolates to… CONTINUE READING
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Efflux pumps in Gram-negative bacteria: what they do how they do it with what and how to deal with them

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