Role of dying endothelial cells in transendothelial macromolecular transport.

@article{Lin1990RoleOD,
  title={Role of dying endothelial cells in transendothelial macromolecular transport.},
  author={Shiow Jiuan Lin and Khalilullah Mia Jan and Shu Chien},
  journal={Arteriosclerosis},
  year={1990},
  volume={10 5},
  pages={703-9}
}
There are focal areas in the aorta with an enhanced endothelial permeability to macromolecules, as indicated by the focal uptake of the protein-binding azo dye Evans blue in vivo. These areas exhibit high rates of endothelial cell turnover and a number of structural characteristics in en face endothelial morphology. To determine the relationship of endothelial cell death to macromolecular leakage at the level of individual endothelial cells, thoracic aortas of 12 adult male Sprague-Dawley rats… CONTINUE READING