Role of dopaminergic and serotonergic systems on behavioral stimulatory effects of low-dose alprazolam and lorazepam
@article{BentuFerrer2001RoleOD, title={Role of dopaminergic and serotonergic systems on behavioral stimulatory effects of low-dose alprazolam and lorazepam}, author={D. Bentu{\'e}-Ferrer and J. M. Reymann and O. Tribut and H. Allain and M. Bourin}, journal={European Neuropsychopharmacology}, year={2001}, volume={11}, pages={41-50} }
Several recent studies have demonstrated that alprazolam and lorazepam, administered at low doses to healthy volunteers, improve cognitive functions and psychomotor performances. Paradoxical effects of low-dose benzodiazepines have been also observed in mice, in experimental pharmacology. The aim of this work was to determine, in rat, the effect of similar low-doses of benzodiazepines on spontaneous locomotor activity and performance in the elevated zero-maze, and to investigate the underlying… CONTINUE READING
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