Role of dopaminergic and serotonergic systems on behavioral stimulatory effects of low-dose alprazolam and lorazepam

@article{BentuFerrer2001RoleOD,
  title={Role of dopaminergic and serotonergic systems on behavioral stimulatory effects of low-dose alprazolam and lorazepam},
  author={D. Bentu{\'e}‐Ferrer and J. Reymann and O. Tribut and H. Allain and E. Vasar and M. Bourin},
  journal={European Neuropsychopharmacology},
  year={2001},
  volume={11},
  pages={41-50}
}
Several recent studies have demonstrated that alprazolam and lorazepam, administered at low doses to healthy volunteers, improve cognitive functions and psychomotor performances. Paradoxical effects of low-dose benzodiazepines have been also observed in mice, in experimental pharmacology. The aim of this work was to determine, in rat, the effect of similar low-doses of benzodiazepines on spontaneous locomotor activity and performance in the elevated zero-maze, and to investigate the underlying… Expand
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