Role of dopamine in the pathophysiology and treatment of obsessive-compulsive disorder.


The differential effects of serotonin-reuptake inhibitors on obsessive-compulsive disorder (OCD) were sufficient to presume that a serotonin regulatory disorder is the most essential part of the pathophysiology of OCD. In patients with OCD, however, a high-dose of serotonin-reuptake inhibitor monotherapy may not be sufficient, and approximately half of… (More)
DOI: 10.1586/ern.09.148


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