Role of different neurotransmitter systems in the cholecystokinin octapeptide-induced anxiogenic response in rats.

@article{Br1997RoleOD,
  title={Role of different neurotransmitter systems in the cholecystokinin octapeptide-induced anxiogenic response in rats.},
  author={Edina B{\'i}r{\'o} and Botond Penke and Gyula Telegdy},
  journal={Neuropeptides},
  year={1997},
  volume={31 3},
  pages={281-5}
}
The possible involvement of different neurotransmitter systems in the anxiogenic action of cholecystokinin octapeptide sulphate ester (CCK-8) was investigated in rats. Intracerebroventricularly (i.c.v.) administered CCK-8 induced an anxiogenic response in an elevated plus-maze test. Pretreatment with dopaminergic, muscarinergic acetylcholine receptor blockers and an opiate receptor antagonist blocked the anxiogenic response to CCK-8. The alpha and beta adrenoreceptor, the GABA receptor and the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…