Role of deregulated microRNAs in non-small cell lung cancer progression using fresh-frozen and formalin-fixed, paraffin-embedded samples.

@article{Wang2016RoleOD,
  title={Role of deregulated microRNAs in non-small cell lung cancer progression using fresh-frozen and formalin-fixed, paraffin-embedded samples.},
  author={Yahong Wang and Jie Chen and Ziying Lin and Jun Cao and Haili Huang and Ying Jiang and Huijuan He and Lawei Yang and Nina Y Ren and Gang Liu},
  journal={Oncology letters},
  year={2016},
  volume={11 1},
  pages={801-808}
}
Non-small cell lung cancer (NSCLC) is responsible for the highest number of cancer-associated mortalities worldwide, and the five-year survival rate is <15% following the initial diagnosis. MicroRNAs (miRNAs) serve important functions in a number of human diseases, including cancer. The present study investigated the expression status, clinical relevance and functional role of miRNA in NSCLC. miRNA expression profiling was performed in lung adenocarcinoma and adjacent unaffected lung tissues… CONTINUE READING
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