Role of dendritic cells in enhancement of herpes simplex virus type 1 latency and reactivation in vaccinated mice.

@article{Mott2008RoleOD,
  title={Role of dendritic cells in enhancement of herpes simplex virus type 1 latency and reactivation in vaccinated mice.},
  author={Kevin R. Mott and Homayon Ghiasi},
  journal={Clinical and vaccine immunology : CVI},
  year={2008},
  volume={15 12},
  pages={1859-67}
}
Ocular infection with herpes simplex virus type 1 (HSV-1) frequently leads to recurrent infection, which is a major cause of corneal scarring. Thus, the prevention of the establishment of latency should be a primary goal of vaccination against HSV-1. To this end, we have examined the contribution of dendritic cells (DCs) to the efficacy of a vaccine against ocular HSV-1 infection. Transgenic mice (expressing a CD11c-diphtheria toxin receptor-green fluorescent protein construct) with a BALB/c… CONTINUE READING

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Ocular infection with herpes simplex virus type 1 ( HSV-1 ) frequently leads to recurrent infection , which is a major cause of corneal scarring .
Ocular infection with herpes simplex virus type 1 ( HSV-1 ) frequently leads to recurrent infection , which is a major cause of corneal scarring .
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