Role of cytoplasmic thioltransferase in cellular regulation by thiol-disulphide interchange.

@article{Mannervik1980RoleOC,
  title={Role of cytoplasmic thioltransferase in cellular regulation by thiol-disulphide interchange.},
  author={Bengt Mannervik and Kent Axelsson},
  journal={The Biochemical journal},
  year={1980},
  volume={190 1},
  pages={125-30}
}
Cytoplasmic thioltransferase purified from rat liver [Axelsson, Eriksson & Mannervik (1978) Biochemistry 17, 2978--2984] catalyses the formation and decomposition of mixed disulphides of proteins and glutathione. The enzyme was found to catalyse the reversible thiol-disulphide interchange between glutathione disulphide and a crude thiol-containing protein fraction from rat liver. This finding indicates a role of the thioltransferase in the regulation of the 'glutathione status' of the cell… CONTINUE READING
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