Role of cytokines in the pathogenesis and suppression of thyroid autoimmunity.

  title={Role of cytokines in the pathogenesis and suppression of thyroid autoimmunity.},
  author={Balaji B. Ganesh and Palash Bhattacharya and Anupama Gopisetty and Bellur S Prabhakar},
  journal={Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research},
  volume={31 10},
Autoimmune thyroid diseases (AITD) are one of the most common organ-specific autoimmune disorders, of which Hashimoto's thyroiditis (HT) and Graves' disease (GD) are 2 of the most common clinical expressions. HT is characterized by hypothyroidism that results from the destruction of the thyroid by thyroglobulin-specific T cell-mediated autoimmune response. In contrast, GD is characterized by hyperthyroidism due to excessive production of thyroid hormone induced by thyrotropin receptor-specific… CONTINUE READING
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