Role of cytokines and oxidative stress in the pathophysiology of acute pancreatitis: therapeutical implications.

@article{GmezCambronero2002RoleOC,
  title={Role of cytokines and oxidative stress in the pathophysiology of acute pancreatitis: therapeutical implications.},
  author={Luis G G{\'o}mez-Cambronero and Lu{\'i}s Sabater and Javier Pereda and Norberto Cassinello and Bruno Camps and J. Vi{\~n}a and Juan Sastre},
  journal={Current drug targets. Inflammation and allergy},
  year={2002},
  volume={1 4},
  pages={393-403}
}
Severe acute pancreatitis causes a high incidence of mortality due to the systemic inflammatory response syndrome leading to multiple organ failure. At present, there is no treatment against severe acute pancreatitis, other than supportive critical care. The relationship between pancreatic injury and the uncontrolled systemic response is not completely understood. Nevertheless, experimental and clinical evidences have shown that pro-inflammatory cytokines and oxidative stress are critically… CONTINUE READING
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