Role of corticotrophin-releasing factor in effects of leptin on sympathetic nerve activity and arterial pressure.

@article{Correia2001RoleOC,
  title={Role of corticotrophin-releasing factor in effects of leptin on sympathetic nerve activity and arterial pressure.},
  author={Marcelo Lima de Gusm{\~a}o Correia and Donald A Morgan and Jennifer L. Mitchell and William I Sivitz and Allyn L. Mark and William Geoffrey Haynes},
  journal={Hypertension},
  year={2001},
  volume={38 3},
  pages={384-8}
}
Leptin and corticotrophin-releasing factor increase sympathetic nervous activity to interscapular brown adipose tissue, kidneys, and adrenal glands. Leptin is known to increase hypothalamic corticotrophin-releasing factor. In this study, we tested the hypothesis that leptin-dependent increases in sympathetic nervous activity are mediated through increases in central nervous system corticotrophin-releasing factor activity. We examined the effects of intracerebroventricular administration of… CONTINUE READING

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