Role of complement activation in acute kidney injury

  title={Role of complement activation in acute kidney injury},
  author={Julio Pascual},
Acute kidney injury has an estimated incidence of 14.9–49.6 per 1000 patient years and may affect 13–18% of hospitalized patients. The incidence is increasing, and it is expected to double over the next decade [1–3]. AKI has been considered a self-limiting disease, with good prognosis when recovery is noted during admission [4], but several studies demonstrated that survivors of AKI may experience considerable late decline in kidney function. Recent studies suggested that AKI episodes are… CONTINUE READING