Role of coagulase in a murine model of hematogenous pulmonary infection induced by intravenous injection of Staphylococcus aureus enmeshed in agar beads.

@article{Sawai1997RoleOC,
  title={Role of coagulase in a murine model of hematogenous pulmonary infection induced by intravenous injection of Staphylococcus aureus enmeshed in agar beads.},
  author={Terumitsu Sawai and Kazunori Tomono and Katsunori Yanagihara and Yukio Yamamoto and Mitsuo Kaku and Yoichi Hirakata and Hiroyasu Koga and Takayoshi Tashiro and Shigeru Kohno},
  journal={Infection and immunity},
  year={1997},
  volume={65 2},
  pages={466-71}
}
We describe a novel mouse model of acute staphylococcal pneumonia induced by intravenous injection of Staphylococcus aureus enmeshed in agar beads. For comparison, we also used various strains of bacteria, including three strains of S. aureus, two strains of Staphylococcus epidermidis, one strain of Streptococcus pyogenes, three strains of Pseudomonas aeruginosa, and one strain of Klebsiella pneumoniae. All except two strains of S. aureus were cleared rapidly from the lungs. When S. aureus… CONTINUE READING

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