Role of cilia, mucus, and airway surface liquid in mucociliary dysfunction: lessons from mouse models.

@article{Mall2008RoleOC,
  title={Role of cilia, mucus, and airway surface liquid in mucociliary dysfunction: lessons from mouse models.},
  author={M. Mall},
  journal={Journal of aerosol medicine and pulmonary drug delivery},
  year={2008},
  volume={21 1},
  pages={
          13-24
        }
}
  • M. Mall
  • Published 2008
  • Medicine
  • Journal of aerosol medicine and pulmonary drug delivery
  • Mucociliary clearance is an important primary innate defense mechanism that protects the lungs from deleterious effects of inhaled pollutants, allergens, and pathogens. Mucociliary dysfunction is a common feature of chronic airway diseases in humans. The mucociliary apparatus consists of three functional compartments, that is, the cilia, a protective mucus layer, and an airway surface liquid (ASL) layer, which work in concert to remove inhaled particles from the lung. A synopsis of clinical and… CONTINUE READING
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