Role of cilia, mucus, and airway surface liquid in mucociliary dysfunction: lessons from mouse models.

@article{Mall2008RoleOC,
  title={Role of cilia, mucus, and airway surface liquid in mucociliary dysfunction: lessons from mouse models.},
  author={Marcus Alexander Mall},
  journal={Journal of aerosol medicine and pulmonary drug delivery},
  year={2008},
  volume={21 1},
  pages={
          13-24
        }
}
  • M. Mall
  • Published 8 March 2008
  • Biology, Medicine
  • Journal of aerosol medicine and pulmonary drug delivery
Mucociliary clearance is an important primary innate defense mechanism that protects the lungs from deleterious effects of inhaled pollutants, allergens, and pathogens. Mucociliary dysfunction is a common feature of chronic airway diseases in humans. The mucociliary apparatus consists of three functional compartments, that is, the cilia, a protective mucus layer, and an airway surface liquid (ASL) layer, which work in concert to remove inhaled particles from the lung. A synopsis of clinical and… 

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