Role of chromatin and transcriptional co-regulators in mediating p63-genome interactions in keratinocytes

Abstract

The Transcription Factor (TF) p63 is a master regulator of epidermal development and differentiation as evident from the remarkable skin phenotype of p63 mouse knockouts. Furthermore, ectopic expression of p63 alone is sufficient to convert simple epithelium into stratified epithelial tissues in vivo and p63 is required for efficient transdifferentiation of… (More)
DOI: 10.1186/1471-2164-15-1042

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