Role of cholesterol in lipid raft formation: lessons from lipid model systems.

@article{Silvius2003RoleOC,
  title={Role of cholesterol in lipid raft formation: lessons from lipid model systems.},
  author={John R Silvius},
  journal={Biochimica et biophysica acta},
  year={2003},
  volume={1610 2},
  pages={174-83}
}
Biochemical and cell-biological experiments have identified cholesterol as an important component of lipid 'rafts' and related structures (e.g., caveolae) in mammalian cell membranes, and membrane cholesterol levels as a key factor in determining raft stability and organization. Studies using cholesterol-containing bilayers as model systems have provided… CONTINUE READING