Role of cholecystokinin in the anorexia produced by duodenal delivery of oleic acid in rats.

@article{Woltman1995RoleOC,
  title={Role of cholecystokinin in the anorexia produced by duodenal delivery of oleic acid in rats.},
  author={Todd Woltman and Daniel Alexander Castellanos and Roger D Reidelberger},
  journal={The American journal of physiology},
  year={1995},
  volume={269 6 Pt 2},
  pages={R1420-33}
}
To assess the importance of triglyceride digestion products in producing satiety, we determined the effects of duodenal infusions of triolein, oleic acid, and oleic acid plus monoolein on meal patterns in ad libitum-feeding rats. Oleic acid and oleic acid plus monoolein inhibited feeding similarly; triolein's effect was delayed and fourfold less potent. We then used the type A cholecystokinin (CCK-A)-receptor antagonist devazepide to assess the importance of CCK in mediating the anorexia… CONTINUE READING

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