Role of chloride-mediated inhibition in respiratory rhythmogenesis in an in vitro brainstem of tadpole, Rana catesbeiana.

@article{Galante1996RoleOC,
  title={Role of chloride-mediated inhibition in respiratory rhythmogenesis in an in vitro brainstem of tadpole, Rana catesbeiana.},
  author={Raymond J Galante and Leszek Kubin and Alfred P. Fishman and Allan I. Pack},
  journal={The Journal of physiology},
  year={1996},
  volume={492 ( Pt 2)},
  pages={545-58}
}
1. The isolated brainstem of larval Rana catesbeiana maintained in vitro generates neural bursts that correspond to the lung and gill ventilatory activity generated in the intact specimen. To investigate the role of chloride channel-dependent inhibitory mechanisms mediated by GABA(A) and/or glycine receptors on fictive lung and gill ventilation, we superfused the isolated brainstems with agonists, antagonists (bicuculline and/or strychnine) or a chloride-free solution while recording multi-unit… CONTINUE READING