Role of chemokines in endocrine autoimmune diseases.

  title={Role of chemokines in endocrine autoimmune diseases.},
  author={Mario Rotondi and Luca Chiovato and Sergio Romagnani and Mario Serio and Paola Romagnani},
  journal={Endocrine reviews},
  volume={28 5},
Chemokines are a group of peptides of low molecular weight that induce the chemotaxis of different leukocyte subtypes. The major function of chemokines is the recruitment of leukocytes to inflammation sites, but they also play a role in tumoral growth, angiogenesis, and organ sclerosis. In the last few years, experimental evidence accumulated supporting the concept that interferon-gamma (IFN-gamma) inducible chemokines (CXCL9, CXCL10, and CXCL11) and their receptor, CXCR3, play an important… CONTINUE READING
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