Role of charge screening and delocalization for lipophilic cation permeability of model and mitochondrial membranes.

@article{Trendeleva2013RoleOC,
  title={Role of charge screening and delocalization for lipophilic cation permeability of model and mitochondrial membranes.},
  author={Tatiana A. Trendeleva and Evgenia I Sukhanova and Anton G Rogov and R. A. Zvyagilskaya and Inna I Seveina and Tatiana M Ilyasova and Dmitry A. Cherepanov and Vladimir P. Skulachev},
  journal={Mitochondrion},
  year={2013},
  volume={13 5},
  pages={
          500-6
        }
}
The effects of the mitochondria-targeted lipophilic cation dodecyltriphenylphosphonium (C12TPP, the charge is delocalized and screened by bulky hydrophobic residues) and those of lipophilic cations decyltriethylammonium bromide and cetyltrimethylammonium bromide (C10TEA and C16TMA, the charges are localized and screened by less bulky residues) on bilayer planar phospholipid membranes and tightly-coupled mitochondria from the yeast Yarrowia lipolytica have been compared. In planar membranes… 
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