Role of cellular lipoteichoic acids in mediating adherence of serotype III strains of group B streptococci to human embryonic, fetal, and adult epithelial cells

@article{Nealon1984RoleOC,
  title={Role of cellular lipoteichoic acids in mediating adherence of serotype III strains of group B streptococci to human embryonic, fetal, and adult epithelial cells},
  author={T. Nealon and S. Mattingly},
  journal={Infection and Immunity},
  year={1984},
  volume={43},
  pages={523 - 530}
}
Lipoteichoic acids (LTA) of serotype III strains of group B streptococci (GBS) were shown to mediate adherence of these organisms to human embryonic (HEC), fetal (HFC), and adult buccal (HBEC) epithelial cells. The binding of GBS was temperature dependent, and maximum attachment occurred at 37 degrees C. HEC, HFC, and HBEC preincubated with purified LTA significantly inhibited attachment of GBS, whereas the group B and type III antigens had no effect. Under phosphate-limiting conditions in… Expand
Kinetic and chemical analyses of the biologic significance of lipoteichoic acids in mediating adherence of serotype III group B streptococci
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Adherence of group B streptococci to adult and neonatal epithelial cells mediated by lipoteichoic acid
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A role for the lipid portion of lipoteichoic acid in the adherence of different serotypes of group B streptococci to vaginal and neonatal epithelial cells is suggested. Expand
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Comparative analysis of the localization of lipoteichoic acid in Streptococcus agalactiae and Streptococcus pyogenes
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Attachment of group B streptococci to macrophages is mediated by a 21-kDa protein.
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A 21-kDa protein from the envelope of GBS type III that directly binds to macrophages is identified as determined by Western blot analysis and may be important in mediating the attachment of Group B Streptococcus in an opsonin-poor environment. Expand
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TLDR
It is suggested that protein involvement, rather than LTA, is primarily responsible for mediating virulent S. agalactiae type III attachment to these synchronously growing, subconfluent eucaryotic monolayers in vitro. Expand
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The protein nature of these structures was proved by a significant reduction of adherence after pretreatment of GBS with trypsin or pepsin, demonstrating the thermosensitivity of the GBS structures involved. Expand
The role of lipoteichoic acid and the leukocyte integrins in the binding of group B streptococci to murine peritoneal macrophages
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Sialic acid levels and lag time of growth in chemically defined medium containing 200 mM phosphate among strains of various serotypes of Streptococcus agalactiae
TLDR
This study carried out a study to ascertain whether strains exhibited a lag time of growth in a chemically defined medium containing 200 mM phosphate, which has been suggested to be characteristic of strains with high lipoteichoic acid levels. Expand
Cell growth rate regulates expression of group B Streptococcus type III capsular polysaccharide
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TLDR
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