Role of cells and mediators in exercise-induced bronchoconstriction.


A susceptible group of subjects with asthma develops airflow obstruction in response to the transfer of water out of the airways during exercise. The transfer of water or the challenge with a hypertonic solution serves as a strong stimulus to the airway epithelium. Susceptible subjects have epithelial shedding into the airway lumen, and airway inflammation… (More)
DOI: 10.1016/j.iac.2013.02.003


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