Role of cell stress signaling networks in cancer cell death and antitumor immune response following proteotoxic injury inflicted by photodynamic therapy.

@article{Korbelik2018RoleOC,
  title={Role of cell stress signaling networks in cancer cell death and antitumor immune response following proteotoxic injury inflicted by photodynamic therapy.},
  author={Mladen Korbelik},
  journal={Lasers in surgery and medicine},
  year={2018},
  volume={50 5},
  pages={
          491-498
        }
}
The insult delivered by photodynamic therapy (PDT) in treated cells is oxidative stress. The main burden threatening survival of PDT-treated cells is proteotoxic damage that jeopardizes proteostasis in these cells. For dealing with this type of proteostasis impairment, cells have developed protection mechanisms operating by signaling networks. This review… CONTINUE READING