Role of cell cycle-associated proteins in microglial proliferation in the axotomized rat facial nucleus.

Abstract

We analyzed cell cycle-associated proteins, including cyclins, cyclin-dependent protein kinases (Cdks), and Cdk inhibitors (CdkIs) in the axotomized rat facial nucleus. Immunoblotting revealed that cyclin A and cyclin D are induced 3-5 days after transection. The induced cyclin A was immunohistochemically recognized in microglia. Cdk2 and Cdk4 were also… (More)
DOI: 10.1002/glia.22291

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