Role of cell adhesion molecules in brain injury after transient middle cerebral artery occlusion in the rat

@article{Matsuo1994RoleOC,
  title={Role of cell adhesion molecules in brain injury after transient middle cerebral artery occlusion in the rat},
  author={Y. Matsuo and H. Onodera and Y. Shiga and H. Shozuhara and M. Ninomiya and T. Kihara and T. Tamatani and M. Miyasaka and K. Kogure},
  journal={Brain Research},
  year={1994},
  volume={656},
  pages={344-352}
}
Activated neutrophils appear to be directly involved in tissue injury after focal cerebral ischemia and reperfusion. Intercellular adhesion molecules-1 (ICAM-1) and CD11/CD18 integrins have been implicated in ischemia-reperfusion induced neutrophil endothelial adhesion and transmigration. We therefore investigated the roles of CD11a/CD18 (LFA-1) and ICAM-1 in cerebral ischemia-reperfusion injury by using monoclonal antibodies, WT1 (anti-CD11a), WT3 (anti-CD18), and 1A29 (anti-ICAM-1). Rats were… Expand
Platelet–Leukocyte–Endothelial Cell Interactions after Middle Cerebral Artery Occlusion and Reperfusion
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