Role of cathepsins in blastocyst hatching in the golden hamster.

@article{Sireesha2008RoleOC,
  title={Role of cathepsins in blastocyst hatching in the golden hamster.},
  author={G. Sireesha and Robert W. Mason and M. A. Hassanein and Sarah Tonack and Alexander Navarrete Santos and Bernd Fischer and Polani B. Seshagiri},
  journal={Molecular human reproduction},
  year={2008},
  volume={14 6},
  pages={337-46}
}
The mammalian embryo is encased in a glycoproteinaceous coat, the zona pellucida (ZP) during preimplantation development. Prior to implantation, the blastocyst must undergo 'hatching' or ZP escape. In hamsters, there is a thinning of the ZP followed by a focal lysis and a complete dissolution of the ZP during blastocyst hatching. Earlier studies from our laboratory have indicated a role for cysteine proteases in the hatching phenomenon. In this study, we tested the effect of specific inhibitors… CONTINUE READING
15 Citations
53 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 53 references

Similar Papers

Loading similar papers…