Role of cardiac chloride currents in changes in action potential characteristics and arrhythmias.

@article{Hiraoka1998RoleOC,
  title={Role of cardiac chloride currents in changes in action potential characteristics and arrhythmias.},
  author={Masayasu Hiraoka and Seiko Kawano and Yuji Hirano and Tetsushi Furukawa},
  journal={Cardiovascular research},
  year={1998},
  volume={40 1},
  pages={23-33}
}
Various types of Cl- currents have been recorded in cardiac myocytes from different regions of the heart and in different species. With few exceptions, most of these currents are not active under basal conditions, but are activated under the influence of various agonists and by physical stress. These channels are distributed nonuniformly, depending on the cell type, tissue and region of the heart. Therefore, Cl- current activation may influence membrane potential and impulse formation… CONTINUE READING

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