Role of cardiac chloride currents in changes in action potential characteristics and arrhythmias.

  title={Role of cardiac chloride currents in changes in action potential characteristics and arrhythmias.},
  author={Masayasu Hiraoka and Seiko Kawano and Yuji Hirano and Tetsushi Furukawa},
  journal={Cardiovascular research},
  volume={40 1},
Various types of Cl- currents have been recorded in cardiac myocytes from different regions of the heart and in different species. With few exceptions, most of these currents are not active under basal conditions, but are activated under the influence of various agonists and by physical stress. These channels are distributed nonuniformly, depending on the cell type, tissue and region of the heart. Therefore, Cl- current activation may influence membrane potential and impulse formation… CONTINUE READING

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Publications referenced by this paper.
Showing 1-10 of 93 references

Cardiovasc Res 1996;32:52–61. tion to volume regulation

J Tranum-Jensen, MJ Janse, JWT Fiolet
Am J Physiol Cell Physiol • 1998

Molecular in the isolated porcine heart

D Duan, C Winter, S Cowley, Hume, B Horowitz
Circ Res • 1998

Chloride channels: an emerging molecular picture.

BioEssays : news and reviews in molecular, cellular and developmental biology • 1997

Erratum appears in ion transport pathways in cardiac myocytes

T Furukawa, T Ogura, +3 authors MJ Lab
Cardiovasc Res FEBS Lett • 1997

Heterogeneity of the ferret papillary muscle

Benitah J-P, AM Gomez, P Bailly
J Physiol ( Lond ) • 1997

Regions involved in

S Grunder, A Thiemann, M Pusch, TJ Jentsch
Am J Physiol • 1997

The osmolar load , membrane damage , and reperfusion

T Ehara, H Matsuoka

porcine heart. Circ Res 1981;49:364–381. identification of a volume-regulated chloride

RB Jennings, KA Reimer, C. Steenbergen

Cardiac swellinginduced chloride current picture

TJ Jentsch, W Gunther, Du X-Y, S Sorota
Circ Res ion Neurobiol • 1996

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