Role of carbonic anhydrases in skin wound healing

@inproceedings{Barker2017RoleOC,
  title={Role of carbonic anhydrases in skin wound healing},
  author={Harlan Barker and Marleena Aaltonen and Peiwen Pan and Maria V{\"a}h{\"a}tupa and Pirkka Kaipiainen and U. S. A. May and Stuart Prince and Hannele Uusitalo-J{\"a}rvinen and Abdul Rais Abdul Waheed and Silvia Pastorekov{\'a} and William S. Sly and Seppo Parkkila and Tero AH J{\"a}rvinen},
  booktitle={Experimental &Molecular Medicine},
  year={2017}
}
Skin wound closure occurs when keratinocytes migrate from the edge of the wound and re-epithelialize the epidermis. Their migration takes place primarily before any vascularization is established, that is, under hypoxia, but relatively little is known regarding the factors that stimulate this migration. Hypoxia and an acidic environment are well-established stimuli for cancer cell migration. The carbonic anhydrases (CAs) contribute to tumor cell migration by generating an acidic environment… CONTINUE READING
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