Role of calcium channels and adenylate cyclase in the PACAP-induced adrenal catecholamine secretion.

Abstract

We elucidated the functional contribution of voltage-dependent calcium channels (VDCCs) and adenylate cyclase to epinephrine (Epi) and norepinephrine (NE) secretion induced by pituitary adenylate cyclase-activating polypeptide (PACAP) in the isolated perfused rat adrenal gland. PACAP increased Epi and NE output, which was inhibited by perfusion with calcium… (More)

Topics

5 Figures and Tables

Slides referencing similar topics