Role of cAMP-Dependent Protein Kinase on Acute Picrotoxin-Induced Seizures


cAMP-dependent protein kinase (PKA) is a major modulator of synaptic transmission likely to be involved in molecular and cellular events leading to epileptogenesis, but little is known about how it affects the onset of acute epileptic seizures. In this study, we determined PKA enzymatic activity in the rat hippocampus during picrotoxin-induced seizures… (More)
DOI: 10.1007/s11064-005-2748-3


4 Figures and Tables