Role of c-Jun N-terminal kinase activation in blastema formation during planarian regeneration.

@article{Tasaki2011RoleOC,
  title={Role of c-Jun N-terminal kinase activation in blastema formation during planarian regeneration.},
  author={Junichi Tasaki and Norito Shibata and Toshihide Sakurai and Kiyokazu Agata and Yoshihiko Umesono},
  journal={Development, growth & differentiation},
  year={2011},
  volume={53 3},
  pages={
          389-400
        }
}
The robust regenerative abilities of planarians absolutely depend on a unique population of pluripotent stem cells called neoblasts, which are the only mitotic somatic cells in adult planarians and are responsible for blastema formation after amputation. Little is known about the molecular mechanisms that drive blastema formation during planarian regeneration. Here we found that treatment with the c-Jun N-terminal kinase (JNK) inhibitor SP600125 blocked the entry of neoblasts into the M-phase… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 30 CITATIONS

Simple blood-feeding method for live imaging of gut tube remodeling in regenerating planarians.

  • Development, growth & differentiation
  • 2016
VIEW 11 EXCERPTS
CITES METHODS & BACKGROUND
HIGHLY INFLUENCED

Molecular mechanisms of limb regeneration: insights from regenerating legs of the cricket Gryllus bimaculatus.

  • The International journal of developmental biology
  • 2018
VIEW 2 EXCERPTS
CITES BACKGROUND

Regenerative response of different regions of Drosophila imaginal discs.

  • The International journal of developmental biology
  • 2018
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 49 REFERENCES

Molecular analysis of stem cells and their descendants during cell turnover and regeneration in the planarian Schmidtea mediterranea

G. T. Eisenhoffer, H. Kang, A. Sánchez Alvarado
  • Cell Stem Cell
  • 2008
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Similar Papers

Loading similar papers…